Patent · US Expired

Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors

US7718776B2 · kind B2 · utility

23Cited by
87References
50Claims
0Family size

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Key dates

Filing dateApr 7, 2003
Grant dateMay 18, 2010
Priority date
Expiry dateApr 7, 2023

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/56
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.