Patent · US Active

Method and device for sample preparation

US7722820B2 · kind B2 · utility

4Cited by

22References

22Claims

0Family size

Assignee

PHYNEXUS, INC. · US

Inventors

Douglas T. Gjerde · Saratoga, US
Allen Burge · Sunnyvale, US
Ronald Jones · Mountain View, US
Mark Abel · San Jose, US

Key dates

Filing date	Nov 21, 2005
Grant date	May 25, 2010
Priority date	—
Expiry date	Sep 9, 2028

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/255
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column, often between two frits. In some embodiments, the extraction columns employ modified pipette tips as column bodies. In some embodiments, the invention provides methods characterized by the use of hydrophobic and/or hydrophilic membranes as frits, and/or by the inclusion of a wad of fibrous material to act as a wicking agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.