Patent · US Active

Antibody molecules and nucleic acids

US7722869B2 · kind B2 · utility

0Cited by

6References

18Claims

0Family size

Assignee

Novartis AG · CH

Inventors

James Burnie · Alderley Edge, GB
Philipp Wechner · Innsbruck, AT

Key dates

Filing date	Apr 24, 2008
Grant date	May 25, 2010
Priority date	—
Expiry date	Apr 24, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/21
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An scFv peptide comprising a VH domain and a VL domain linked by an amino acid spacer is disclosed. The VH domain comprises a sequence with at least 80% sequence identity to the sequence of SEQ ID NO. 64. The VL domain comprises a sequence with at least 80% sequence identity to the sequence of SEQ ID NO. 66. The scFv peptide also comprises the substitution or deletion of an amino acid in the VH domain at the position corresponding to C28.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.