Patent · US Active

Immunoglobulins devoid of light chains

US7722871B2 · kind B2 · utility

24Cited by

14References

11Claims

0Family size

Assignee

VRIJE UNIVERSITEIT BRUSSEL · BE

Inventors

Cecile Casterman · Sint-Genesius-Rode, BE
Raymond Hamers · Sint-Genesius-Rode, BE

Key dates

Filing date	Feb 10, 2006
Grant date	May 25, 2010
Priority date	—
Expiry date	Jul 28, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to an immunoglobulin having determined antigen specificity, and having a variable fragment which is obtainable from a camelid heavy-chain immunoglobulin having two heavy polypeptide chains capable of recognizing and binding an antigen and which is further devoid of polypeptide light chains, wherein the immunoglobulin having determined antigen specificity is devoid of a CH1 constant region between the variable region and the hinge region and has within its constant region at least part of a constant region of a human antibody.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.