Use of azetidinone compounds
US7723020B2 · kind B2 · utility
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40References
6Claims
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Key dates
| Filing date | Oct 25, 2006 |
| Grant date | May 25, 2010 |
| Priority date | — |
| Expiry date | Oct 25, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4704
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.