Biochips including ion transport detecting structures and methods of use
US7723029B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 15, 2005 |
| Grant date | May 25, 2010 |
| Priority date | — |
| Expiry date | Nov 22, 2026 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/049
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention recognizes that the determination of an ion transport function or property using direct detection methods, such as patch-clamps, whole cell recording or single channel recording, are preferable to methods that utilize indirect detection methods, such as FRET based detection system. The present invention provides biochips and methods of use that allow for the direct analysis of ion transport functions or properties using microfabricated structures that can allow for automated detection of one or more ion transport functions or properties. These biochips and methods of use thereof are particularly appropriate for automating the detection of ion transport functions or properties, particularly for screening purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.