Screening assay for macromolecules that inhibit binding of sulfated glycosaminoglycan to beta amyloid
US7723057B1 · kind B1 · utility
1Cited by
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3Claims
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Key dates
| Filing date | Mar 30, 1999 |
| Grant date | May 25, 2010 |
| Priority date | — |
| Expiry date | Mar 30, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6896
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A screening assay for selecting macromolecules that interfere with the binding of a sulfated GAG to beta amyloid, the assay comprising affixing a sulfated GAG to a substrate, co-incubating the macromolecule and a known amount of beta amyloid with the sulfated GAG, determining the amount of beta amyloid bound to the sulfated GAG affixed to the substrate; wherein the macromolecule will be one which interferes with the binding of the sulfated GAG to beta amyloid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.