Gene cluster involved in safracin biosynthesis and its uses for genetic engineering
US7723068B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 2003 |
| Grant date | May 25, 2010 |
| Priority date | — |
| Expiry date | Jan 3, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/182
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ ID NO:1, variants or portions thereof, or at least one of the sacA, sacB, sacC, sacC, sacD, sacE, sacF, sacG, sacH, sacH, saI, sacJ, orf1, orf2, orf3 or orf4 genes, including variants or portions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.