Nucleic acid molecules for enhanced production of a bacterial polysaccharide and methods of use thereof
US7723087B2 · kind B2 · utility
12Cited by
30References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 12, 2003 |
| Grant date | May 25, 2010 |
| Priority date | — |
| Expiry date | May 7, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/31
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to nucleic acid sequences and related compositions for producing over-expression of the polysaccharide PNAG of Staphylococci. PNAG may be isolated and formulated into vaccines or used to generate antibodies. Binding agents of the nucleic acids are also described. The invention also relates to diagnostic and therapeutic methods using the compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.