Means for detecting pathological transformation of the APP protein and their uses
US7723117B2 · kind B2 · utility
7Cited by
2References
26Claims
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Key dates
| Filing date | Nov 5, 2001 |
| Grant date | May 25, 2010 |
| Priority date | — |
| Expiry date | Feb 3, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Pathological modifications of the APP protein can be detected in a sample by use of markers consisting of catabolic and/or metabolic fragments of the carboxyl-terminal part of the APP (APP-Cter fragments) resulting from a neurodegenerative condition wherein the APP participates in the etiology. Methods for detecting such markers provide diagnostic and therapeutic applications in degenerative pathologies such as Alzheimer's Disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.