Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation

US7723306B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Stefan Bassarab · Biberach, DE
• Karoline Bechtold-Peters · Biberach, DE
• Richard Fuhrherr · Uetersen, DE
• Wolfgang Friess · Iffeldorf, DE
• Patrick Garidel · Norderstedt, DE
• Torsten Schultz-Fademrecht · Maselheim, DE

Key dates

• Filing date: May 2, 2005
• Grant date: May 25, 2010
• Expiry date: Jun 17, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/47
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a spray-dried powder and method for its manufacture. A spray dried powder containing a pharmaceutical active substance and one or more 1,4 O-linked saccharose derivatives chosen from the compounds: 1,4 O-linked D-gal-saccharose (lactosucrose), 1,4 O-linked D-glu-saccharose (glucosyl sucrose) or 1,4 O-linked glu-glu-saccharose (maltosyl sucrose). Preferred combinations are such that they contain glucosyl and maltosyl sucrose.