Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof

US7723536B2 · kind B2 · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Amos B. Smith, III · Yeadon, US
• Thomas Beauchamp · Portage, US
• Matthew J. LaMarche · Reading, US
• Yuping Qiu · Princeton Junction, US
• Michael Kaufman · Ypsilanti, US
• Hirokazu Arimoto · Sendai, JP
• David Jones · Milford, US
• Kaoru Kobayashi · Osaka, JP

Key dates

• Filing date: Feb 28, 2008
• Grant date: May 25, 2010
• Expiry date: Apr 13, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.