Devices, methods, and kits for non-invasive glucose measurement

US7725149B2 · kind B2 · utility

Inventors

• Thomas A. Peyser · Menlo Park, US
• Russell O. Potts · San Francisco, US
• Herbert L. Berman · Los Altos Hills, US
• James W. Moyer · San Francisco, US
• Mikhail Kouchnir · Sunnyvale, US

Key dates

• Filing date: Jun 22, 2005
• Grant date: May 25, 2010
• Expiry date: Oct 27, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2562/0295
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.