Reagent stripe for test strip

US7727467B2 · kind B2 · utility

Assignees

• Roche Diagnostics Operations, Inc. · US
• Roche Operations Ltd. · BM

Inventors

• David W. Burke · Bay City, US
• Michael Marquant · Mannheim, DE
• Udo Zapf · Speyer, DE
• Michael Fritz · Biblis, DE
• Dan Mosoiu · Schifferstadt, DE
• Chris Wilsey · Carmel, US

Key dates

• Filing date: Jun 18, 2004
• Grant date: Jun 1, 2010
• Expiry date: Nov 19, 2027

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T156/1084
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.