Methods and compounds for the treatment of mucus hypersecretion
US7727538B2 · kind B2 · utility
17Cited by
11References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2006 |
| Grant date | Jun 1, 2010 |
| Priority date | — |
| Expiry date | Jul 15, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating mucus hypersecretion, the causative factor in chronic obstructive pulmonary disease (COPD), asthma and other clinical conditions involving COPD, comprises administering a compound that inhibits exocytosis in mucus secreting cells or neurones that control or direct mucus secretion. Also described is a compound, for use in the treatment of hypersecretion of mucus, which inhibits mucus secretion by inhibiting mucus secretion by mucus secreting cells, and/or inhibiting neurotransmitter release from neuronal cells controlling or directing mucus secretion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.