Powder comprising new compositions of oligosaccharides and methods for their preparation

US7727962B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Stefan Bassarab · Biberach, DE
• Karoline Bechtold-Peters · Biberach, DE
• Richard Fuhrherr · Uetersen, DE
• Wolfgang Friess · Iffeldorf, DE
• Patrick Garidel · Norderstedt, DE
• Torsten Schultz-Fademrecht · Maselheim, DE

Key dates

• Filing date: May 2, 2005
• Grant date: Jun 1, 2010
• Expiry date: Apr 21, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/715
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention concerns powders containing a pharmaceutical active substance and a combination of excipients comprising at least one 1,4 O-linked saccharose derivative selected from the compounds: 1,4 O-linked D-Gal-saccharose (lactosucrose), 1,4 O-linked D-Glu-saccharose (glucosyl sucrose), or 1,4 O-linked Glu-Glu-saccharose (maltosyl sucrose) in combination with at least one further excipient. The other excipient is preferably an amino acid, a peptide and/or a mono-, di- and/or oligosaccharide, wherein the oligosaccharide may be a second 1,4 O-linked saccharose derivative, provided that this is different from the first.