Nucleotide primer set and nucleotide probe for detecting genotype of methylene tetrahydrofolate reductase (MTHFR)
US7728119B2 · kind B2 · utility
8Cited by
2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 2008 |
| Grant date | Jun 1, 2010 |
| Priority date | — |
| Expiry date | Jan 17, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6827
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
There is provided is a nucleotide primer set for LAMP amplification used for detecting genotypes of single-nucleotide polymorphisms C677T and A1298C of an MTHFR gene. There is also provided a nucleotide probe for detecting an amplification product amplified by the primer set according to the present invention. There is also provided a method of detecting the genotypes of the single-nucleotide polymorphisms C677T and A1298C in the MTHFR gene, by using the primer set according to the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.