Method for the asymmetric synthesis of beta-lactone compounds
US7728153B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 2006 |
| Grant date | Jun 1, 2010 |
| Priority date | — |
| Expiry date | Feb 22, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91057
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.