Method for capturing charged molecules traveling in a flow stream

US7731827B2 · kind B2 · utility

Assignees

• PerkinElmer Health Sciences, Inc. · US
• BIOMOTIF AB · SE
• Hans Jornvall · SE

Inventors

• Juan Astorga-Wells · Älta, SE
• Sang-Ryoul Park · Daejeon, KR
• Harold Swerdlow · Witham, GB
• Gerald Jesson · Säter, SE
• Ulf Lindberg
• Tomas Bergman · Järfälla, SE
• Hans Jornvall · Stockholm, SE
• Mats Jonsson · Uppsala, SE

Key dates

• Filing date: Jun 17, 2005
• Grant date: Jun 8, 2010
• Expiry date: Apr 8, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2001/4016
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to a method for capturing charged molecules of interest traveling in an electrolyte flow stream through an electrically non-conductive channel, comprising at least one anode and at least one cathode individually separated from said channel, but in electrical contact with said flow stream, by a conductive ion selective semi-permeable membrane. Said membrane interferes with the normal migration of ions towards its respective electrode, generating at least two zones of different electric field. Balance between hydrodynamic and electrical forces captures certain ions into the flow stream. it also relates to a device for performing the method.