Compositions for inducing immune responses
US7731967B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 29, 2004 |
| Grant date | Jun 8, 2010 |
| Priority date | — |
| Expiry date | Apr 29, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides, inter alia, immunogenic compositions comprising a first antigen, at least two adjuvants, wherein a first adjuvant comprises a polymer derived from poly(lactides) and/or poly(lactide-co-glycolides), and wherein a second adjuvant comprises an imidazoquinoline, wherein said first antigen is encapsulated within, adsorbed or conjugated to, co-lyophilized or mixed with said first adjuvant, and a pharmaceutically acceptable excipient, wherein said composition elicits a cellular immune response when administered to a vertebrate subject. The invention also provides methods of producing immunogenic compositions, methods for producing a cytotoxic-T lymphocyte (CTL) response in a vertebrate subject, and methods of immunization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.