Dynamic monitoring of cell adhesion and spreading using the RT-CES system
US7732127B2 · kind B2 · utility
43Cited by
58References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 27, 2005 |
| Grant date | Jun 8, 2010 |
| Priority date | — |
| Expiry date | Sep 27, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/0257
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention includes devices and methods for dynamically monitoring cell adhesion and cell spreading. Cells are added to a microelectronic cell sensor array operably connected to an impedance analyzer. The device also includes a coating including biological molecule or organic compound capable of interacting with the cell. Cell adhesion and cell mobility is determined by detecting changes in impedance and comparing impedance or cell index values between samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.