Patent · US Active

Recombinant methods and materials for producing epothilone and epothilone derivatives

US7732186B2 · kind B2 · utility

0Cited by

33References

10Claims

0Family size

Assignee

Kosan Biosciences Incorporated · US

Inventors

Bryan Julien · Oakland, US
Leonard Katz · Oakland, US
Chaitan Khosla · Stanford, US
Li Tang · Beijing, CN
Rainer Ziermann · San Mateo, US

Key dates

Filing date	Oct 31, 2007
Grant date	Jun 8, 2010
Priority date	—
Expiry date	Feb 11, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P17/181
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Recombinant nucleic acids that encode all or a portion of the epothilone polyketide synthase (PKS) are used to express recombinant PKS genes in host cells for the production of epothilones, epothilone derivatives, and polyketides that are useful as cancer chemotherapeutics, fungicides, and immunosuppressants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.