Medicinal uses of mu-opioid receptor agonists
US7732398B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 29, 2006 |
| Grant date | Jun 8, 2010 |
| Priority date | — |
| Expiry date | Nov 18, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods for stimulating mu-opioid receptors with agonist peptides in a mammal in need thereof. The methods comprise administering to the mammal an effective amount of a selective mu-opioid receptor agonist peptide that comprises at least two α-amino acid residues. At least one of the amino acid residues has a positive charge. The amino acid residue in the first position is a tyrosine or tyrosine derivative. The amino acid in the second position is a D-α-amino acid. The present invention also provides methods of treating a mammal suffering from conditions or diseases by administering to the mammal an effective amount of the peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.