Combinations of transfection lipids exhibiting increased transfection efficiencies
US7732420B2 · kind B2 · utility
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4References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 4, 2004 |
| Grant date | Jun 8, 2010 |
| Priority date | — |
| Expiry date | May 29, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/88
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides optimized transfection reagents comprising mixtures of cationiclipoids. In particular, the present invention provides DNA delivery vehicles based on identifying the optimal hydrophobicity of novel cationic phospholipid derivatives that, alone or in combination, form complexes with DNA (lipoplexes) and exhibit enhanced transfection activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.