Patent · US Active

2-(amino-substituted)-4-aryl pyrimidines and related compounds useful for treating inflammatory diseases

US7732444B2 · kind B2 · utility

24Cited by

8References

19Claims

0Family size

Assignee

Millennium Pharmaceuticals, Inc. · US

Inventors

Paul E. Fleming · Wellesley, US
Zhan Shi · Concord, US
Brendan Chen · Sudbury, US
Jane Schmidt · South San Francisco, US
John Charles Reader · Princeton, US
Neal D. Hone · Brighton, GB
Jeffrey P. Ciavarri · Reading, US

Key dates

Filing date	Jan 10, 2005
Grant date	Jun 8, 2010
Priority date	—
Expiry date	Dec 5, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A heterocyclic inhibitor having the formula I, with the variables defined herein, which is useful for treating inflammatory and other physiological disorders in which PKC-theta isoform plays a role:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.