Substituted thiophene carboxamides, process for their preparation and their use as medicaments

US7732466B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Roland Pfau · Biberach, DE
• Henning Priepke · Warthausen, DE
• Kai Gerlach · Biberach, DE
• Wolfgang Wienen · Äpfingen, DE
• Annette Schuler-Metz · Ulm, DE
• Herbert Nar · Ochsenhausen, DE
• Sandra Handschuh · Biberach an der Riß, DE
• Georg Dahmann · Biberach an der Riß, DE

Key dates

• Filing date: May 10, 2005
• Grant date: Jun 8, 2010
• Expiry date: Oct 20, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to new substituted thiophene-2-carboxylic acid amides of general formulawherein A, and R1 to R8c are defined as in claim 1, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.