Patent · US Active

Modified bacteriocins and methods for their use

US7732586B2 · kind B2 · utility

9Cited by
6References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 14, 2007
Grant dateJun 8, 2010
Priority date
Expiry dateMay 23, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/74
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Modified forms of naturally occurring bacteriocins, such as the R-type pyocins of Pseudomonas aeruginosa, are disclosed. The bacteriocins are modified at the ends of their tail fibers in a region responsible for binding specificity and affinity to their cognate binding partners, or receptors, such as those on the surface of bacteria. Methods for the use of the modified bacteriocins, such as to bind receptors, including virulence or fitness factors, on the surfaces of bacteria, are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.