Method of treating cancer by administering conjugates comprising human IL-18 and substitution mutants thereof
US7736639B2 · kind B2 · utility
5Cited by
2References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2007 |
| Grant date | Jun 15, 2010 |
| Priority date | — |
| Expiry date | Dec 21, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of treating cancer in patients in need thereof with human interleukin-18 (IL-18) polypeptides and substitution mutants thereof that are conjugated to water-soluble polymers at specific sites on the human IL-18 protein are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.