Enzyme-based time temperature indicator
US7736866B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 3, 2005 |
| Grant date | Jun 15, 2010 |
| Priority date | — |
| Expiry date | Mar 31, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N31/229
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A time temperature indicator for indicating temperature change over time is provided, comprising an immobilized enzyme and a substrate of the enzyme, wherein the reaction of the substrate catalyzed by the enzyme produces a reaction product in a time and temperature dependent manner and wherein the formation of the reaction product can be detected by monitoring a physical characteristic of the substrate and/or the product which is linked to its concentration. Also provided is a method of time temperature indication comprising the step of an enzyme-catalyzed reaction, a method of printing the enzyme-based time temperature indicator on a packaging material or a label, a printing ink or printing ink concentrate comprising components of the enzyme-based time temperature indicator and a packaging material or a label comprising the enzyme-based time temperature indicator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.