Patent · US Active

Composition for enzyme inhibition

US7737112B2 · kind B2 · utility

53Cited by
8References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 7, 2005
Grant dateJun 15, 2010
Priority date
Expiry dateDec 19, 2027

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.