Patent · US Active

Methods for the specific preparation of lysobactin fragments

US7737120B2 · kind B2 · utility

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1References

8Claims

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Assignee

AiCuris GmbH & Co. KG · DE

Inventors

Franz Von Nussbaum · Mülheim an der Ruhr, DE
Werner Schroeder · Bleichheim, DE
Chantal Fuerstner · Neheim, DE

Key dates

Filing date	May 4, 2007
Grant date	Jun 15, 2010
Priority date	—
Expiry date	Sep 11, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K7/06
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to methods for the targeted production of lysobactin derivatives by combined chemical and enzymatic modifications. In particular, the invention relates to method for preparing lysobactin fragment 4-11 by chemical reduction and cleavage of the resultant product by chymotrypsin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.