Methods and systems for generating and evaluating peptides
US7739055B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 17, 2006 |
| Grant date | Jun 15, 2010 |
| Priority date | — |
| Expiry date | Mar 5, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B50/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods to create databases of peptides having a desirable property, such as antimicrobial activity, involving analyzing a database of known peptides for a pattern statistically associated with the desirable property are described herein, The set of sequences being analyzed may include sequences of a desired length containing all or substantially all combinations of amino acids that conform to at least one of the set of patterns. Once the database is identified, the database may be processed in a pattern recognition procedure that identifies a set of patterns that may be representative of a peptide having the desirable property. A set of newly generated peptides sequences may then be processed to score these new sequences against the identified patterns to correlate the patterns to the sequences and determine a degree of association or similarity between one or more of the new sequences and the set of identified patterns.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.