Capillary-channeled polymeric fiber as solid phase extraction media
US7740763B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2006 |
| Grant date | Jun 22, 2010 |
| Priority date | — |
| Expiry date | Nov 14, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Solid phase extraction devices including a plurality of packed nominally aligned capillary-channeled polymeric fibers for use as stationary phase materials are disclosed. A plurality of fibers are packed together in a casing so as to provide good flow characteristics through the fibers and high surface area contact between a sample and the fibers. Different polymer compositions of the fibers permit the “chemical tuning” of the extraction process. The fibers can be physically or chemically derivatized to target specific analytes for separation from a test sample. Use of the fibers allows a wide range of liquid flow rates with very low backpressures. The fibers are easily packed into a micropipette tip or a conduit for use with a fluid flow device such as an aspirator or a pump. The devices can be used for isolation and pre-concentration of analytes from samples, for instance for proteins from buffer solutions or extraction of pollutants from remote locations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.