Anaerobic bacterium as a drug for cancer gene therapy
US7740835B2 · kind B2 · utility
16Cited by
12References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 23, 2004 |
| Grant date | Jun 22, 2010 |
| Priority date | — |
| Expiry date | Feb 23, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/01
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a bacterium belonging to the genus Bifidobacterium, by which DNA coding for a protein having an antitumor activity or DNA coding for a protein having the activity of converting a precursor of an antitumor substance into the antitumor substance is delivered to tumor tissues specifically under anaerobic conditions thereby expressing the protein encoded by the DNA, as well as a pharmaceutical composition comprising said anaerobic bacterium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.