Variant Fc regions
US7740847B2 · kind B2 · utility
47Cited by
42References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 2005 |
| Grant date | Jun 22, 2010 |
| Priority date | — |
| Expiry date | Jan 29, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/734
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides humanized anti-CD20 antibodies comprising a human IgG1 Fc region comprising an isoleucine at position 247 and a glutamine at position 339 as well as nucleic acids encoding the antibodies and methods of using the antibodies for treating lymphoma. Furthermore, the invention provides compositions comprising the antibodies and methods of producing them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.