Patent · US Active

Azonafide derivatives, methods for their production and pharmaceutical compositions therefrom

US7741337B2 · kind B2 · utility

1Cited by

1References

4Claims

0Family size

Assignee

Unibioscreen S.A. · BE

Inventors

Eric Van Quaquebeke · Woluwe-Saint-Lambert - Sint-Lambrechts-Woluwe, BE
Jerome Tuti · Jemeppe-sur-Sambre, BE
Laurent Van den Hove · Forest, BE
Robert Kiss · South San Francisco, US
Francis Darro · Malmedy, BE

Key dates

Filing date	Nov 9, 2006
Grant date	Jun 22, 2010
Priority date	—
Expiry date	Dec 10, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention is directed to azonafide derivatives obtained by reacting azonafide with aldehydes, acyl halides, thioacyl halides, monoisocyanates, isothiocyanates, sulfonyl halides, monohalogenoalkanes, monohalogenoalkenes or monohalogenoalkynes, and are useful as active ingredients of pharmaceutical compositions for the prevention and treatment of cell proliferative disorders, in particular several forms of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.