Patent · US Active

Antibodies to GM-CSF

US7741450B2 · kind B2 · utility

17Cited by

14References

6Claims

0Family size

Assignee

MORPHOTEK, INC. · US

Inventors

Philip M. Sass · Audubon, US
Nicholas C. Nicolaides · Boothwyn, US
Luigi Grasso · Via Enrico Fermi, US
Jian Li · Fort Washington, US
Qimin Chao · Havertown, US
Eric Routhier · Glen Mills, US
Wolfgang Ebel · Conshohocken, US

Key dates

Filing date	Feb 8, 2007
Grant date	Jun 22, 2010
Priority date	—
Expiry date	Feb 15, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.