Long lasting fusion peptide inhibitors for HIV infection

US7741453B2 · kind B2 · utility

Assignee

• Conjuchem Biotechnologies, Inc. · CA

Inventors

• John W. Erickson · Barrington, US
• Dominique P. Bridon · Morton Grove, US
• Martin Robitaille · Gatineau, CA
• Grant A. Krafft · Glenview, US
• Dong Xie · Beijing, CN
• Elena Afonina · Franklin Lakes, US
• Jun Liang · Los Altos Hills, US
• Sandra DeMeyer · Beerse, BE

Key dates

• Filing date: May 31, 2002
• Grant date: Jun 22, 2010
• Expiry date: Aug 14, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16122
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to C34 peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory syncytial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections.