Anti-sclerostin antibodies
US7744874B2 · kind B2 · utility
22Cited by
5References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 2008 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Mar 11, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.