Use of islet 1 as a marker for isolating or generating stem cells
US7745113B2 · kind B2 · utility
24Cited by
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15Claims
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Key dates
| Filing date | Feb 2, 2004 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Nov 12, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides in vitro methods of expansion and propagation of undifferentiated progenitor cells and more specifically undifferentiated progenitor cells containing Islet1, a marker apparently unique to proliferating cardiac stem cells. Methods are described for isolation of stem cell populations as well as for provoking expansion and propagation of undifferentiated progenitor cells without differentiation, to provide cardiac repair or improve cardiac function, for example.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.