Molecular diagnostic method for dementia with lewy bodies
US7745127B2 · kind B2 · utility
0Cited by
0References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 2005 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Sep 4, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2814
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.