Process for the biological production of 1,3-propanediol with high yield
US7745184B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 24, 2008 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Jul 5, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the cofactor requirements necessitates the use of a whole cell catalyst for an industrial process that utilizes this reaction sequence to produce 1,3-propanediol. The invention provides a microorganism with disruptions in specified genes and alterations in the expression levels of specified genes that is useful in a higher yielding process to produce 1,3-propanediol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.