Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network
US7745221B2 · kind B2 · utility
54Cited by
160References
32Claims
0Family size
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Key dates
| Filing date | Aug 27, 2004 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Jun 26, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/2575
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on an optical switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.