Amyloid binding assays
US7745222B2 · kind B2 · utility
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6References
13Claims
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Key dates
| Filing date | Oct 13, 2006 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Dec 24, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4709
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein are amyloid-binding assays that simulate in situ brain conditions by combining binders with various A-beta species on mammalian brain tissue. In general the amyloid-binding assays comprise the steps of (a) contacting a mammalian brain tissue sample with at least one A-beta species; (b) applying a putative binder to the brain tissue sample; and (c) determining whether the putative binder binds to the A-beta species.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.