Patent · US Active

Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues

US7745392B2 · kind B2 · utility

0Cited by

2References

22Claims

0Family size

Assignee

NITTO DENKO CORPORATION · JP

Inventors

Zheng Hou · San Diego, US
Jian Liu · Los Angeles, US
Lei Yu · Huangguan, CN

Key dates

Filing date	Sep 21, 2006
Grant date	Jun 29, 2010
Priority date	—
Expiry date	Dec 4, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K7/64
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are guanidinium containing compounds consisting of a core moiety with a plurality of side chains containing guanidinium groups. Such compounds have enhanced translocation across cellular membranes and epithelial tissues. The compounds may also have a therapeutic or other biologically active moiety attached so that these moieties may be effectively transported into a cell by the guanidinium containing compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.