Indene derivatives and process for the preparation thereof
US7745439B2 · kind B2 · utility
1Cited by
2References
3Claims
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Key dates
| Filing date | Apr 12, 2005 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | May 10, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.