Thieno-[2,3-d]pyrimidine and thieno-pyridazine compounds and methods of use
US7745449B2 · kind B2 · utility
2Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2007 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Apr 25, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula Iwherein A1, A2, B, R2 and R3 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.