Antibody and immunoassays for determining the presence of Δ9-Tetrahydrocannabinol
US7749772B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 29, 2006 |
| Grant date | Jul 6, 2010 |
| Priority date | — |
| Expiry date | Nov 6, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Antibodies having specific binding for the parent THC (Δ9-THC) and its major metabolites are provided which present a significant increase in sensitivity of immunoassays such as lateral flow immunoassays and ELISA for THC. The present invention also provides a rabbit hybridoma producing the antibody as a monoclonal antibody, a recombinant antibody, further molecularly engineered recombinant antibodies against parent Δ9-THC and its metabolites and cell lines producing the recombinant antibodies. The invention also provides applications of the antibody in immunoassays, particularly lateral flow immunoassays, specifically applications in detecting THC in body fluids, particularly saliva, and kits for determining the presence of THC.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.