Pharmaceutical composition comprising FGF18 and IL-1 antagonist and method of use
US7749965B2 · kind B2 · utility
5Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 2008 |
| Grant date | Jul 6, 2010 |
| Priority date | — |
| Expiry date | Apr 15, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
FGF18 is known to stimulate the proliferation of chondrocytes, bone, and nervous tissue, resulting in repair of diseased tissue. When an IL-1 antagonist is administered in addition to FGF18, the effects on the IL-1 mediated disease and also, the effect on cartilage, bone, and nervous cell proliferation, are found to be greater than administration of FGF18 or the IL-1 antagonist alone. The present invention encompasses a pharmaceutical composition that combines FGF18 with IL-1 antagonist and methods of treating IL-1 mediated disease using this pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.