Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation
US7750012B2 · kind B2 · utility
8Cited by
2References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 3, 2006 |
| Grant date | Jul 6, 2010 |
| Priority date | — |
| Expiry date | Sep 6, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formulaThey are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.